On the origin of the nucleus: a hypothesis

https://pmc.ncbi.nlm.nih.gov/articles/PMC10732040/

Related to The Vital Question — eukaryogenesis and the origin of the nucleus.

Proposes a model for the archaeal origin of the nucleus. Discusses:

• The eukaryotic nucleoplasm and cytoplasm as distinct regions of a common compartment
• Phylogenetic and experimental data showing archaeal counterparts to eukaryotic nuclear machines
• Cell biology of TACK and Asgardarchaeota (closest archaeal relatives of eukaryotes)
• Predictions that can be tested